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Test Code Lab38 Tobramycin, Trough, Plasma

Methodology

Enzyme Immunoassay

 

Literature References:

Package insert: Tobramycin TOBR2. Roche Diagnostics, 02/2015.

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Specimen Requirements

Specimen Type: Plasma
Container/Tube: Mint-green top (lithium heparin)
Specimen Volume: Full tube
 

Collection Instructions: Draw blood no earlier than 60 minutes prior to dose. Trough level for first dose should be drawn just prior to next dose.

Additional Information: Date and time of draw are required.

Specimen Transport Temperature

Ambient

Reference Values

Setting Target Range
Unspecified indication <2 mcg/mL
UTI/GPC synergy* <2 mcg/mL
Systemic illness <2 mcg/mL
Sepsis <2 mcg/mL
Physician alert value (automatic call-back) ≥ 2.1 mcg/mL

*UTI/GPC synergy refers to the synergistic effect of aminoglycosides with other antibiotics in treating urinary tract infections caused by gram-positive cocci (eg, Enterococcus).

 

Day(s) Test Set Up

Monday through Sunday
Turnaround Time:
STAT: 1 hour
Routine: 2-4 hours

Test Classification and CPT Coding

80200-Tobramycin

 

Additional Information

For BJH Laboratory Use Only

Alternate Tube(s):

1 dark green-top (lithium or sodium heparin) tube

1 red-top tube

1 lavender-top (EDTA) tube

Separator gel tube is acceptable.

 

Analyte Stability:

  • Specimens must be processed within 8 hours.
  • Processed sample stability:
    • Ambient - 8 hours
    • Refrigerated (2 - 8°C) - 3 days
    • Frozen (≤ -20°C) - 1 month
  • See Analyte Stability Chart under General Information for a complete list.

Laboratory Processing Instructions:

Test performed in BJH Core Lab.  Processed by automated line for delivery to the Cobas 8000. Completed specimens are stored refrigerated for 5 days.

LOINC Code Information

Name LOINC Code
Tobramycin, Trough, Plasma 4059-2