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Test Code LAB5414 VerifyNow Clopidogrel (P2Y12) Screening Test

Methodology

Turbidimetric Based Optical Detection System 

Note: The assay detects inhibition of platelet aggregation due to irreversible binding of clopidogrel to platelet P2Y12 ADP receptors.

Literature Reference:

Package insert: VerifyNow P2Y12, 14353.D. Accumetrics, Inc, 04/27/2009.

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Specimen Requirements

Call Barnes Jewish Hospital Hematology Laboratory Customer Service at 314-362-1470 to obtain 2, 2-mL Griener Bio-One Vacuette tubes. 

 

Specimen Type: Sodium citrate plasma

Container/Tube: 2-mL Griener Bio-One Vacuette tubes

Specimen Volume: 2 Full tubes

Collection Instructions: 

1. Do not centrifuge. Clotted blood or an insufficient specimen is not acceptable.

2. Avoid hemolysis and heparin contamination of specimen.  

 

Collection Procedure:

Attention to collection procedure is necessary to avoid inaccurate results, collect as follows:

1. Draw a discard tube (volume depends on type of venous access).

2. Draw 2 Griener blue-top tubes. Do not overfill or under fill.

3. Forward promptly at ambient temperature. Do not send Greiner blue-top tube through the pneumatic tube system.

Specimen Transport Temperature

Ambient

Reference Values

Reference interval from adults not taking aspirin is 169-356 PRU.

Literature Reference:

Prabhakaran S, Wells KR, Lee VH, Flaherty CA, Lopes DK. Prevalence and risk factors for aspirin and clopidogrel resistance in cerebrovascular stenting. (Published November 7, 2007 as 10.317/ajnr.A0818, www.ajnr.org.)

Day(s) Test Set Up

Monday through Sunday
Turnaround Time:
STAT: not available 
Routine: 2-4 hours after receipt in laboratory

Test Classification and CPT Coding

85576

Additional Information

 

 

For BJH Laboratory Use Only
Alternate Tube(s):None

 

Analyte Stability:

4 hours at ambient temperature.

Laboratory Processing Instructions:

Test performed in BJH Core Lab.