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Test Code LAB492 Protein S, Free, Plasma

Important Note

ALIAS: Protein S Antigen

Methodology

Immunoturbidimetric

Literature References:

HemosIL Free Protein S (pn20002700) Instrumentation Laboratory, package insert issued 02/2016.

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Specimen Requirements

Specimen Type: Blood

Container/Tube: Light-blue top (citrate)
Specimen Volume: Full tube
Specimen Minimum Volume: Full tube
Collection Instructions:

  1. Draw a discard blue top tube prior to drawing a light-blue top (citrated) tube if using a Winged Infusion Set.  Discard tube should be under filled and discarded.
  2. Clotted blood or an insufficient specimen is not acceptable.
  3. Avoid phlebotomy techniques which cause hemolysis and heparin contamination.
  4. Follow nursing policy on volume of blood to discard prior to collecting blood from indwelling heparinized catheters.

Analyte Stability:

4 hours at 18° C to 24° C.

Platelet-free plasma can be frozen at -20 for transport on dry ice up to 72 hours
or stored 6 months at -70° C.


Additional Information: If the patient is a hospital patient and the hematocrit is >55%, call Barnes-Jewish Hematology Laboratory at 314-362-5203 for instructions.

Specimen Transport Temperature

Ambient Yes/Refrigerate NO/Frozen Yes

 

Reference Values

55%-160%

Numerous drugs and clinical conditions affect the plasma concentration of the protein.

Literature References:

1. Wolf M, Boyer-Neumann C, Peynaud D, et al. Clinical applications of a direct assay of free protein S antigen using monoclonal antibodies. A study of 59 cases. Blood Coag Fibrinolysis 1994;5:187-92.

2. Lane DA, Mannucci PM, Bauer KA, et al. Inherited thrombophilia: part 1. Thromb Haemostasis 1996;76:651-62.

Day(s) Test Set Up

 

Monday, Wednesday, and Friday

Cut-off time: 0700

Turnaround Time:

STAT: not available

Routine: results available the day of testing

Test Classification and CPT Coding

85306

Additional Information

For BJH Laboratory Use Only

Analyte Stability:

4 hours at 18o C to 24° C.

Platelet-free plasma can be frozen at -20 for transport on dry ice up to 72 hours
or stored 6 months at -70° C.

Laboratory Processing Instructions:
Test performed in BJH Core Lab.

LOINC Code Information

Name LOINC Code
Protein S, Free, Plasma 4677-1