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Test Code CREAT Creatinine, Plasma

Performing Laboratory

NRL-Chemistry

Methodology

Rate/Colorimetric

Includes calculation of the estimated glomerular filtration rate (eGFR).

Calculation using CKD-EPI 2021 study equation:

GFR = 142 min (standardized Scr/K, 1)α x max (standardized Scr/K, 1) -1.200 x 0.9938 Age x 1.012 [if female]

The equation requires three variables:

  • Serum, or plasma, creatinine (Scr)
  • Age in years (18 years or older)
  • Gender (male or female)
  • Race is not included when using the BJC Cerner eGFR calculation.

Note: This test is also available as part of #BMP Basic Metabolic Panel, #COMP Comprehensive Metabolic Panel, and  #RENAL Renal Function Panel. See Common Panel Test Combinations in Special Instructions to avoid duplicate test requests when multiple panels are ordered.

Specimen Requirements

Specimen Type: Plasma

Container/Tube: Light-green top (lithium heparin)

Specimen Volume: 2 mL

Collection Instructions: Avoid hemolysis.

Reference Values

CREATININE

Males
0-4yrs: 0.10-0.50 mg/dL
4-20yrs: 0.20-1.20 mg/dL
≥20yrs: 0.70-1.40 mg/dL
Females
0-4yrs: 0.10-0.50 mg/dL
4-20yrs: 0.20-1.20 mg/dL
≥20yrs: 0.60-1.30 mg/dL

 

eGFR

Reference Interval 
Normal                            >/= 90 mL/min/1.73m2 
Mildly decreased*                 60 - 89 mL/min/1.73m2 
Mildly to moderately decreased    45 - 59 mL/min/1.73m2 
Moderately to severely decreased  30 - 44 mL/min/1.73m2 
Severely decreased                15 - 29 mL/min/1.73m2 
Kidney Failure                    < 15  mL/min/1.73m2 
*Relative to young adult level 

Estimated glomerular filtration rate is determined by the 2021 CKD-EPI equation recommended by the National Kidney Foundation (A Unifying Approach to GFR Estimation: Recommendations of the NKF-ASK Task Force on Reassessing the Inclusion of Race in 
Diagnosing Kidney Disease, JASN 2021). The CKD-EPI equation should not be used for patients with unstable renal function and has not been validated in children and those over 70. 
 

 

Day(s) Test Set Up

Monday through Sunday

Turnaround Time:

STAT-45 minutes

Routine-shift

Specimen Transport Temperature

Refrigerate

Test Classification and CPT Coding

82565

Special Instructions