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Test Code LMPP Lipoprotein Metabolism Profile, Serum

Reporting Name

Lipoprotein Metabolism Profile

Useful For

Diagnosing dyslipoproteinemia

 

Quantifying cholesterol and triglycerides in very-low-density lipoprotein, low-density lipoprotein (LDL), high-density lipoproteins (HDL), and chylomicrons

 

Identifying lipoprotein-X

 

Classifying hyperlipoproteinemias (lipoprotein phenotyping)

 

Evaluating patients with abnormal lipid values (cholesterol, triglyceride, HDL, LDL) for specific phenotypes

Profile Information

Test ID Reporting Name Available Separately Always Performed
TCS Cholesterol, Total, CDC, S No Yes
TRIGC Triglycerides, CDC, S No Yes
APLBS Apolipoprotein B, S Yes, (order APOLB) Yes
HDLS HDL Cholesterol, CDC, S No Yes
LMPP1 Lipoprotein Metabolism Profile 1 No Yes

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Necessary Information


Patient's age and sex are required.



Specimen Required


Patient Preparation:

1. Fasting-overnight (12-14 hours)

2. Patient must not consume any alcohol for 24 hours before the specimen is collected.

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  60 days

Reference Values

2-9 years

10-17 years

≥18 years

Total cholesterol

*

Acceptable: <170 mg/dL

Borderline high: 170-199 mg/dL

High: ≥200 mg/dL

**

Desirable: <200 mg/dL

Borderline high: 200-239 mg/dL

High: ≥ 240 mg/dL

Triglycerides

*

Acceptable: <75 mg/dL

Borderline high: 75-99 mg/dL

High: ≥100 mg/dL

*

Acceptable: <90 mg/dL

Borderline high: 90-129 mg/dL

High: ≥130 mg/dL

**

Normal: <150 mg/dL

Borderline high: 150-199 mg/dL

High: 200-499 mg/dL

Very high: ≥500 mg/dL

Low-density lipoprotein (LDL) cholesterol

*

Acceptable: <110 mg/dL

Borderline high: 110-129 mg/dL

High: ≥130 mg/dL

***

Desirable: <100 mg/dL

Above Desirable: 100-129 mg/dL

Borderline high: 130-159 mg/dL

High: 160-189 mg/dL

Very high: ≥190 mg/dL

LDL triglycerides

≤50 mg/dL

≤50 mg/dL

Apolipoprotein B

*

Acceptable: <90 mg/dL

Borderline high: 90-109 mg/dL

High: ≥110 mg/dL

***

Desirable: <90 mg/dL

Above Desirable: 90-99mg/dL

Borderline high: 100-119 mg/dL

High: 120-139 mg/dL

Very high: ≥140 mg/dL

High-density lipoprotein (HDL) cholesterol

*

Low: <40 mg/dL

Borderline low: 40-45 mg/dL

Acceptable: >45 mg/dL

***

Males: ≥40mg/dL

Females: ≥50mg/dL

Very low-density lipoprotein (VLDL) cholesterol

<30 mg/dL

<30 mg/dL

VLDL triglycerides

<90 mg/dL

<120 mg/dL

Beta VLDL cholesterol

<15 mg/dL

<15 mg/dL

Beta VLDL

triglycerides

<15 mg/dL

<15 mg/dL

Chylomicron cholesterol

Undetectable

Undetectable

Chylomicron triglycerides

Undetectable

Undetectable

Lp(a) cholesterol

<5 mg/dL

<5 mg/dL

LpX

Undetectable

Undetectable

 

Reference values have not been established for patients who are less than 2 years of age.

*Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents

**National Cholesterol Education Program (NCEP)

***National Lipid Association

Day(s) Performed

Monday through Thursday, Sunday

CPT Code Information

80061-Lipid panel (includes: HDL [CPT Code 83718], total cholesterol [CPT Code 82465], and triglycerides [CPT Code 84478] if all performed)

82172-Apolipoprotein B

83700-Lp(a) cholesterol electrophoresis

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LMPP Lipoprotein Metabolism Profile In Process

 

Result ID Test Result Name Result LOINC Value
TCS Cholesterol, Total, CDC, S 2093-3
HDLS HDL Cholesterol, CDC, S 2085-9
TRIGC Triglycerides, CDC, S 2571-8
APLBS Apolipoprotein B, S 1884-6
2839 LDL Cholesterol 2089-1
2840 LDL Triglycerides 3046-0
2844 VLDL cholesterol 2091-7
2847 VLDL triglycerides 3047-8
2842 Beta VLDL Cholesterol 66499-5
2843 Beta VLDL triglycerides 3045-2
2855 Chylomicron cholesterol 34467-1
2856 Chylomicron triglycerides 35363-1
2849 Lp(a) Cholesterol 35388-8
23924 LpX 42178-4
23937 Interpretation 59462-2

Report Available

2 to 4 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus Reject

Method Name

TCS, TRIGD: Enzymatic Colorimetric

APLBS: Automated Turbidimetric Immunoassay

HDLS: Selective Precipitation, Enzymatic Colorimetric

LMPP1: Ultracentrifugation/Electrophoresis/Automated Enzymatic/Colorimetric Analysis

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Forms

If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen.