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Test Code LAB5139 Mitochondrial Antibodies, Serum

Methodology

Indirect Immunofluorescence

Testing Algorithm:

If mitochondrial antibody is positive, then mitochondrial antibody titer will be performed, at an additional charge.

Literature References:

Package insert Nova Lite ANA Plus mouse kidney and stomach July 2018.

Performing Laboratory

Barnes-Jewish Hospital Laboratory

Specimen Requirements

Specimen Type: Serum

Container/Tube: Plain red top

Specimen Volume: Full tube

 

Specimen Transport Temperature

Ambient

Reference Values

Mitochondrial Antibodies Interpretation
≤1:20 Negative
>1:20 Positive-suggests primary biliary cirrhosis
>1:80 Positive-strong evidence of primary biliary cirrhosis

Literature References:

1. Alvarez F, Berg P, Bianchi F, Bianchi L, Burroughs AK, Cancado EL, et al. International autoimmune hepatitis group report: a review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999;31:929-38.

2. Czaja AJ, Norman GL. Division of Gastroenterology and Hepatology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota and INOVA Diagnostics, San Diego, California. Autoantibodies in the diagnosis and management of liver disease. J Clin Gastroenterol 2003;37:315-29.

Day(s) Test Set Up

Monday, Wednesday, Friday

Cut-off time: 0800

Turnaround Time:
STAT: not available
Routine: results available the day of testing

Test Classification and CPT Coding

86381-Mitochondrial antibody screen
86381-Mitochondrial antibody titer (if appropriate)

Additional Information

For BJH Laboratory Use Only

Alternate Tube:

SST Red top

Gold Top (serum SST)

Laboratory Processing Instructions:

Test performed in BJH Core Lab. Processed by automated line and aliquot stored frozen for batch analysis. Completed specimens are stored refrigerated for 5 days.

Note: #5028 Smooth Muscle Antibodies, Serum is performed on the same slide. If positive, results will be reported at no charge. Titer will not be performed.

LOINC Code Information

Name LOINC Code
Mitochondrial Antibodies, Serum 17284-1